Effect of bioimplants versus autogenous bone graft for sinus augmentation in a rabbit model

Conclusions. There exists the potential to develop a bioimplant which functions at least as well as autogenous bone in sinus augmentation.Results. At 2 weeks, BMP-containing bioimplants produce fine trabecular bone with highly vascular stroma. Histomorphometric analysis of the samples at 2 weeks demonstrated that BMP-containing bioimplants produced the most new bone (p < 0.01). At 8 weeks, there was no difference in the amount of bone produced by the different bioimplants at 8 weeks (p > 0.05).Purpose. To compare the potential use of various bioimplants when used for sinus floor augmentation in a rabbit model.Methods. Bilateral sinus floor augmentation and posterior iliac crest bone harvest procedures were performed in 40 adult rabbits. One of the five different approaches was used (DBM, BMP high dose, BMP low dose, BMP/DBM bioimplants or particulated autogenous bone) to augment each maxillary. They were sacrificed at either 2 or 8 weeks.